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Cochrane Reviews

Sulthiame add-on therapy for epilepsy

Milburn-McNulty, P., et al To compare the efficacy and side-effect profile of sulthiame as add-on therapy compared with placebo or another antiepileptic drug Epilepsy is a common neurological condition which is characterised by recurrent seizures. The maj ...

Non-pharmacological interventions for preventing secondary vascular events after stroke or transient ischemic attack

MacKay-Lyons, M., et al Non-pharmacological interventions, Secondary vascular events, Vascular risk factors, Stroke, Transient ischemic attack (TIA) Stroke is the second leading cause of adult death worldwide. There is increasing evidence that individuals ...

Nidotherapy for people with schizophrenia

Chamberlain, i.J. and Sampson, S. Nidotherapy, Standard care, No treatment, Schizophrenia, Disorders Nidotherapy (from the Latin ‘ nidus ’ or ‘nest’) aims at identifying the need for and making changes to a person’s environment and surroundings. It works ...

Multidimensional rehabilitation programmes for adult cancer survivors

Scott, D.A., et al MDRPs, Physical well-being, Psychosocial well-being, Adult, Cancer survivors Due to improvements in detection, treatment and care an increasing number of patients are living with or surviving cancer. However, patients who survive cancer ...

Inhaled corticosteroids for subacute and chronic cough in adults

Johnstone, K., et al Chronic cough, Adults Persistent cough is a common clinical problem. Despite thorough investigation and empirical management, a considerable proportion of those people with subacute and chronic cough have unexplained cough, for which ...

Human papillomavirus testing versus repeat cytology for triage of minor cytological cervical lesions

Arbyn, M., et al Women, ASCUS, LSIL, Cytological test, High-risk type, Human papillomavirus (hrHPV), Cervical cancer Atypical squamous cells of undetermined significance (ASCUS) and low-grade squamous intra-epithelial lesions (LSIL) are minor lesions of t ...

Computer-based diabetes self-management interventions for adults with type 2 diabetes mellitus

Pal, k., et al Health status, Quality of life, Diabetes, Self-management Diabetes is one of the commonest long-term medical conditions, affecting around 347 million adults worldwide. Around 90% of them have type 2 diabetes and are at significant risk of d ...

Interventions for nail psoriasis

de Vries, A.C.Q., et al Nail psoriasis, Skin disease Psoriasis is a common chronic skin disease with a prevalence in 2% to 3% of the population, according to European studies. Involvement of the nails occurs in about 50%. Nail psoriasis is difficult to tr ...

Antibiotics for exacerbations of chronic obstructive pulmonary disease

Vollenweider, D., et al Antibiotics, Acute COPD exacerbation,Treatment failure, Primary outcome, Mortality, Adverse events, Length of hospital stay Chronic obstructive pulmonary disease (COPD) is a chronic condition, often caused by smoking, which affects ...

Male involvement for increasing the effectiveness of prevention of mother-to-child HIV transmission (PMTCT) programmes

Brusamento, S., et al PMTCT interventions, Developing countries, Family health During the past ten years, national governments and international agencies have strengthened the implementation of PMTCT programmes. However, the majority of women still do not ...

Integration of HIV/AIDS services with maternal, neonatal and child health, nutrition, and family planning services

Lindegren, M., et al MNCHN-FP, HIV/AIDS, Prevention, Treatment Integrating HIV/AIDS prevention and treatment services with services focused on the health of mothers, infants and children, as well as on nutrition and family planning (MNCHN-FP) may improve ...

Psychological interventions for symptomatic management of non-specific chest pain in patients with normal coronary anatomy

Kisely, S.P. et al Chest pain Recurrent chest pain in the absence of coronary artery disease is a common problem that sometimes leads to excess use of medical care. Although many studies examine the causes of pain in these patients, few clinical trials ha ...

Low-fat diets for acquired hypercholesterolaemia

Smart, N.A. et al Hypercholesterolaemia Hypercholesterolaemia, characterised by raised blood cholesterol levels, is not a disease itself but a metabolic derangement that often contributes to many diseases, notably cardiovascular disease. In most cases, el ...

Chinese herbal medicines for hypercholesterolemia

Lan Lui, Z. et al Chinese medicine Hypercholesterolemia is an important key contributory factor for ischemic heart disease and is associated with age, high blood pressure, a family history of hypercholesterolemia, and diabetes. Chinese herbal medicines ha ...

Artichoke leaf extract for treating hypercholesterolaemia

Wider, B. et al Hypercholesterolaemia Hypercholesterolaemia is directly associated with an increased risk for coronary heart disease and other sequelae of atherosclerosis. Artichoke leaf extract (ALE) has been implicated in lowering cholesterol levels. Wh ...

Reduced or modified dietary fat for preventing cardiovascular disease

Hooper, L. et al Heart disease Reduction and modification of dietary fats have differing effects on cardiovascular risk factors (such as serum cholesterol), but their effects on important health outcomes are less clear. The objective of this review is to ...

Reduced dietary salt for the prevention of cardiovascular disease

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Omega 3 fatty acids for prevention and treatment of cardiovascular disease

Hooper, L. et al Heart disease It has been suggested that omega 3 (W3, n-3 or omega-3) fats from oily fish and plants are beneficial to health. The objective of this review is to assess whether dietary or supplemental omega 3 fatty acids alter total morta ...

Multiple risk factor interventions for primary prevention of coronary heart disease

Ebrahim, S. et al Heart disease Multiple risk factor interventions using counselling and educational methods assumed to be efficacious and cost-effective in reducing coronary heart disease (CHD) mortality and morbidity and that they should be expanded. Tr ...

Dietary advice for reducing cardiovascular risk

Brunner, E. et al Heart disease Changes in population diet are likely to reduce cardiovascular disease and cancer, but the effect of dietary advice is uncertain. The objective of this review is to assess the effects of providing dietary advice to achieve ...

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