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Systematic reviews

Psychological interventions for symptomatic management of non-specific chest pain in patients with normal coronary anatomy

Kisely, S.P. et al Chest pain Recurrent chest pain in the absence of coronary artery disease is a common problem that sometimes leads to excess use of medical care. Although many studies examine the causes of pain in these patients, few clinical trials ha ...

Low-fat diets for acquired hypercholesterolaemia

Smart, N.A. et al Hypercholesterolaemia Hypercholesterolaemia, characterised by raised blood cholesterol levels, is not a disease itself but a metabolic derangement that often contributes to many diseases, notably cardiovascular disease. In most cases, el ...

Chinese herbal medicines for hypercholesterolemia

Lan Lui, Z. et al Chinese medicine Hypercholesterolemia is an important key contributory factor for ischemic heart disease and is associated with age, high blood pressure, a family history of hypercholesterolemia, and diabetes. Chinese herbal medicines ha ...

Artichoke leaf extract for treating hypercholesterolaemia

Wider, B. et al Hypercholesterolaemia Hypercholesterolaemia is directly associated with an increased risk for coronary heart disease and other sequelae of atherosclerosis. Artichoke leaf extract (ALE) has been implicated in lowering cholesterol levels. Wh ...

Reduced or modified dietary fat for preventing cardiovascular disease

Hooper, L. et al Heart disease Reduction and modification of dietary fats have differing effects on cardiovascular risk factors (such as serum cholesterol), but their effects on important health outcomes are less clear. The objective of this review is to ...

Reduced dietary salt for the prevention of cardiovascular disease

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Omega 3 fatty acids for prevention and treatment of cardiovascular disease

Hooper, L. et al Heart disease It has been suggested that omega 3 (W3, n-3 or omega-3) fats from oily fish and plants are beneficial to health. The objective of this review is to assess whether dietary or supplemental omega 3 fatty acids alter total morta ...

Multiple risk factor interventions for primary prevention of coronary heart disease

Ebrahim, S. et al Heart disease Multiple risk factor interventions using counselling and educational methods assumed to be efficacious and cost-effective in reducing coronary heart disease (CHD) mortality and morbidity and that they should be expanded. Tr ...

Dietary advice for reducing cardiovascular risk

Brunner, E. et al Heart disease Changes in population diet are likely to reduce cardiovascular disease and cancer, but the effect of dietary advice is uncertain. The objective of this review is to assess the effects of providing dietary advice to achieve ...

Antibiotics for brain abscesses in people with cyanotic congenital heart disease

Lumbiganon, P. and Chaikitpinyo, A. Heart disease Brain abscess is a focal, intracerebral infection that begins as a localized area of brain infection and develops into a collection of pus surrounded by a well-vascularized capsule. People with cyanotic co ...

Behavioural and cognitive behavioural therapy for obsessive compulsive disorder in children and adolescents

O'Kearney, R.T., Anstey, K., von Sanden, C. andHunt, A. Obsessive-compulsive disorder (OCD) Background This is an update of a Cochrane Review first published in The Cochrane Library in Issue 4, 2006. Obsessive-compulsive disorder (OCD) in children an ...

Pharmacologic treatment of depression in multiple sclerosis

Koch, M.W. et al Depression Depression is a common problem in patients with multiple sclerosis (MS). It is unclear which pharmacologic treatment is the most effective and the least harmful. The objective of this review is to investigate the efficacy and t ...

Recombinant growth hormone for children and adolescents with Turner syndrome

Baxter, L., Bryant, J., Cave, C.B. and Milne, R. Genetic endocrine disorder Turner syndrome (TS) affects about one in 1500 to 2500 live-born females. One of the most prevalent and salient features of the syndrome is extremely short stature. Untreated wome ...

Smoking cessation for the secondary prevention of coronary heart disease

Critchley, J.A. and Capewell, S. Smoking cessation and coronary heart disease Although the importance of smoking as a risk factor for coronary heart disease is beyond doubt, the speed and magnitude of risk reduction when a smoker with coronary heart disea ...

Routine hospital admission versus out-patient or home care in children at diagnosis of type 1 diabetes mellitus

Clar, C. Waugh, N. and Thomas, S. Treatment of children newly diagnosed with type 1 diabetes In many places, children newly diagnosed with type 1 diabetes mellitus are admitted to hospital for metabolic stabilisation and training, even if they are not acu ...

Continuous subcutaneous insulin infusion (CSII) versus multiple insulin injections for type 1 diabetes mellitus

Masso, M.L. et al Type 1 diabetes Type 1 diabetes is a metabolic disorder resulting from a defect in insulin secretion. Onset of type 1 diabetes mellitus may occur at any age and it is one of the most common chronic diseases of childhood and adolescence. ...

Interventions for latent autoimmune diabetes (LADA) in adults

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Protein restriction for diabetic renal disease

Robertson, L.M., Waugh, N. and Robertson, A. Effects of dietary protein restriction Diabetic renal disease (diabetic nephropathy) is a leading cause of end-stage renal failure. Once the process has started, it cannot be reversed by glycaemic control, but ...

Phosphodiesterase inhibitors for erectile dysfunction in patients with diabetes mellitus

Vardi, M. and Nini, A. Erectile dysfunction and diabetes Erectile dysfunction is a common multi-factorial complication of diabetes mellitus. Numerous strategies have been tried to overcome this diabetic complication. In recent years, phosphodiesterase typ ...

Short acting insulin analogues versus regular human insulin in patients with diabetes mellitus

Siebenhofer, A. et al Insulin treatment Short acting insulin analogue use for diabetic patients is still controversial, as reflected in many scientific debates. The objective of this review is to assess the effects of short acting insulin analogues versus ...

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