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Cochrane Reviews

Pressure relieving interventions for preventing and treating diabetic foot ulcers

Spencer, S. A. Diabetic foot ulcers Foot ulceration is thought to affect 15% of all people with diabetes at some time during their life. The objective of this review is to assess the effectiveness of pressure relieving interventions in the prevention and ...

Silver based wound dressings and topical agents for treating diabetic foot ulcers

Bergin, S. and Wraight, P. Diabetic foot ulcers Foot ulceration affects 15 to 20% of people with diabetes. It is a major precursor to amputation in this patient group, and early and appropriate treatment provides the greatest opportunity for healing. The ...

Hydrogel dressings for healing diabetic foot ulcers

Durnville, J.C., Deshpande, S., O'Meara S. and Speak, K. Diabetic foot ulcers Foot ulcers in people with diabetes are a prevalent and serious global health issue. Dressings form a key part of ulcer treatment, with clinicians and patients having many ...

Honey as a topical treatment for wounds

Jull, A.B., Rodgers, A. and Walker, N. BURN INJURY, INJURY Honey is a viscous, supersaturated sugar solution derived from nectar gathered and modified by the honeybee, Apis mellifera. Honey has been used since ancient times as a remedy in wound care. Evid ...

Granulocyte-colony stimulating factors as adjunctive therapy for diabetic foot infections

Cruciani, M., Lipsky, B., Mengoli, C. and deLalla, F. Diabetic foot infections Granulocyte-colony stimulating factor (G-CSF) increases the release of neutrophil endothelial progenitor cells from the bone marrow and improves neutrophil functions, which are ...

Foam dressings for healing diabetic foot ulcers

Durnville, J.C., Deshpande, S., O'Meara S. and Speak, K. Diabetic foot ulcers Foot ulcers in people with diabetes are a prevalent and serious global health issue. Dressings form a key part of ulcer treatment, with clinicians and patients having many ...

Debridement of diabetic foot ulcers

Edwards, J. and Stapley, S. Diabetic foot ulcers Foot ulceration is thought to affect 15% of people with diabetes at some time in their lives. Debridement is widely regarded as an effective intervention to speed up ulcer healing. The most effective method ...

Vitamin C and superoxide dismutase (SOD) for diabetic retinopathy

de Jesus, C.C.L. et al Effects of vitamin C and superoxide dismutase on diabetic retinopathy There is increasing evidence that diabetic retinopathy is caused by the action of free radicals. Radical scavengers like vitamin C and superoxide dismutase (SOD) ...

Pentoxifylline for diabetic retinopathy

de Jesus, C.C.L. et al Diabetic retinopathy There is increasing evidence that capillary occlusion plays an important part in the development of diabetic retinopathy. Disaggregants, such as pentoxyfilline may influence the outcome and progression of diabet ...

Antiangiogenic therapy with anti-vascular endothelial growth factor modalities for diabetic macular oedema

Parravano, M., Menchini, F. and Virgili, G. Diabetic macular oedema (DMO), Diabetic retinopathy, Vision, Therapy Diabetic macular oedema (DMO) is a common complication of diabetic retinopathy. The retina at the macula thickens and this can cause gradual l ...

Iodine supplementation for preventing iodine deficiency disorders in children

Angermaye, L. and Clar, C. CHILD, MENTAL HEALTH, NUTRITIONAL DEFICIENCY Iodine deficiency is the main cause of potentially preventable mental retardation in childhood, as well as causing goitre and hypothyroidism in people of all ages. It is still prevale ...

Pharmacotherapy for weight loss in adults with type 2 diabetes mellitus

Norris, S.L. et al Weight management Obesity is closely related to type 2 diabetes and long-term weight reduction is an important part of the care delivered to obese persons with diabetes. The objective of this review is to assess the efficacy of pharmaco ...

Long-term non-pharmacological weight loss interventions for adults with type 2 diabetes mellitus

Norris, S.L. et al DIABETES MELLITUS, LIFESTYLE, OBESITY, WEIGHT LOSS, WEIGHT MANAGEMENT Most persons with type 2 diabetes are overweight and obesity worsens the metabolic and physiologic abnormalities associated with diabetes. The objective of this revie ...

Interventions to change the behaviour of health professionals and the organisation of care to promote weight reduction in overweight and obese adults

Flodgren G, Deane K, Dickinson HO, Kirk S, Alberti H, Beyer FR, Brown JG, Penney TL, Summerbell CD, Eccles MP HEALTH INTERVENTION, HEALTH PROFESSIONAL, OBESITY, OVERWEIGHT, WEIGHT MANAGEMENT Although obesity used to be confined largely to high income coun ...

Weight reduction for primary prevention of stroke in adults with overweight or obesity

Curioni C, André C, Veras R Management of overweight and obesity Rigorous scientific evidence linking overweight or obesity with increased risk for stroke is missing. Overweight and obesity are important public health problems and are associated with many ...

Surgery for Obesity

Colquitt JL, Picot J, Loveman E, Clegg AJ Management of overweight and obesity Obesity is associated with many health problems and a higher risk of death. Bariatric (weight loss) surgery for obesity is usually only considered when all other treatments hav ...

Long-term Pharmacotherapy for Obesity and Overweight

Padwal RS, Rucker D, Li SK, Curioni C, Lau DCW OBESITY, OVERWEIGHT, WEIGHT LOSS, WEIGHT MANAGEMENT This review assessed the long-term benefits and risks of approved anti-obesity drugs in clinical trials of 1 to 4 years duration. Sixteen orlistat (10,631 p ...

Exercise for Overweight or obesity

Shaw, K.A., Gennat, H.C., O'Rourke, P. and Del Mar, C. OBESITY, OVERWEIGHT, PHYSICAL ACTIVITY, WEIGHT LOSS, WEIGHT MANAGEMENT Overweight and obesity are important public health problems and are associated with many serious health conditions. The risk ...

Physical activity and enhanced fitness to improve cognitive function in older people without known cognitive impairment

1Research Group Lifestyle and Health, University of Applied Sciences, Utrecht, Netherlands. 2Research Department of Health and Lifestyle, University of Professional Education, Utrecht, Netherlands. 3Department of Geriatric Medicine, University Medical Cen ...

School-based programmes for preventing smoking

Thomas, R. E. and Perera, R. Review of whether school-based programmes are effective in the long term prevention of smoking Smoking rates in adolescents are rising in some countries. Helping young people to avoid starting smoking is a widely endorsed goal ...

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