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Cochrane Reviews

'Human' insulin versus animal insulin in people with diabetes mellitus

Richter, B. and Neisis, G. Insulin treatment Human insulin was introduced for the routine treatment of diabetes mellitus in the early 1980s without adequate comparison of efficacy to animal insulin preparations. First reports of altered hypoglycaemia awar ...

Alpha-glucosidase inhibitors for people with impaired glucose tolerance or impaired fasting blood glucose

Van da Laar, F. et al Alpha-glucosidase inhibitors, Blood glucose Alpha-glucosidase inhibitors (AGIs) reduce blood glucose levels and may thus prevent type 2 diabetes and cardiovascular disease in patients with impaired glucose tolerance (IGT). These poss ...

Antiangiogenic therapy with anti-vascular endothelial growth factor modalities for diabetic macular oedema

Parravano, M., Menchini, F. and Virgili, G. Diabetic macular oedema (DMO), Diabetic retinopathy, Vision, Therapy Diabetic macular oedema (DMO) is a common complication of diabetic retinopathy. The retina at the macula thickens and this can cause gradual l ...

Antibiotics for brain abscesses in people with cyanotic congenital heart disease

Lumbiganon, P. and Chaikitpinyo, A. Heart disease Brain abscess is a focal, intracerebral infection that begins as a localized area of brain infection and develops into a collection of pus surrounded by a well-vascularized capsule. People with cyanotic co ...

Antibiotics for exacerbations of chronic obstructive pulmonary disease

Vollenweider, D., et al Antibiotics, Acute COPD exacerbation,Treatment failure, Primary outcome, Mortality, Adverse events, Length of hospital stay Chronic obstructive pulmonary disease (COPD) is a chronic condition, often caused by smoking, which affects ...

Artichoke leaf extract for treating hypercholesterolaemia

Wider, B. et al Hypercholesterolaemia Hypercholesterolaemia is directly associated with an increased risk for coronary heart disease and other sequelae of atherosclerosis. Artichoke leaf extract (ALE) has been implicated in lowering cholesterol levels. Wh ...

Behavioural and cognitive behavioural therapy for obsessive compulsive disorder in children and adolescents

O'Kearney, R.T., Anstey, K., von Sanden, C. andHunt, A. Obsessive-compulsive disorder (OCD) Background This is an update of a Cochrane Review first published in The Cochrane Library in Issue 4, 2006. Obsessive-compulsive disorder (OCD) in children an ...

Chinese herbal medicines for hypercholesterolemia

Lan Lui, Z. et al Chinese medicine Hypercholesterolemia is an important key contributory factor for ischemic heart disease and is associated with age, high blood pressure, a family history of hypercholesterolemia, and diabetes. Chinese herbal medicines ha ...

Chinese herbal medicines for people with impaired glucose tolerance or impaired fasting blood glucose

Grant, S.J. et al Herbal medicines Around 308 million people worldwide are estimated to have impaired glucose tolerance (IGT); 25% to 75% of these will develop diabetes within a decade of initial diagnosis. At diagnosis, half will have tissue-related dama ...

Cognitive rehabilitation for executive dysfunction in adults with stroke or other adult non-progressive acquired brain damage

Chung, C.S.Y., et al Cognitive rehabilitation, Executive Dysfunction, Adults, Stroke, Non-progressive acquired brain injury Executive function is the term used to describe the brain processes that we use to organise ourselves and solve problems. Executive ...

Complex interventions for preventing diabetic foot ulceration

Dorresteijn, J.A.N., Knegsman, D.M.W. and Valk, G.D. Diabetic foot ulcers Ulceration of the feet, which can lead to the amputation of feet and legs, is a major problem for people with diabetes mellitus, and can cause substantial economic burden. Single pr ...

Computer-based diabetes self-management interventions for adults with type 2 diabetes mellitus

Pal, k., et al Health status, Quality of life, Diabetes, Self-management Diabetes is one of the commonest long-term medical conditions, affecting around 347 million adults worldwide. Around 90% of them have type 2 diabetes and are at significant risk of d ...

Continuous subcutaneous insulin infusion (CSII) versus multiple insulin injections for type 1 diabetes mellitus

Masso, M.L. et al Type 1 diabetes Type 1 diabetes is a metabolic disorder resulting from a defect in insulin secretion. Onset of type 1 diabetes mellitus may occur at any age and it is one of the most common chronic diseases of childhood and adolescence. ...

Debridement of diabetic foot ulcers

Edwards, J. and Stapley, S. Diabetic foot ulcers Foot ulceration is thought to affect 15% of people with diabetes at some time in their lives. Debridement is widely regarded as an effective intervention to speed up ulcer healing. The most effective method ...

Dietary advice for reducing cardiovascular risk

Brunner, E. et al Heart disease Changes in population diet are likely to reduce cardiovascular disease and cancer, but the effect of dietary advice is uncertain. The objective of this review is to assess the effects of providing dietary advice to achieve ...

Effectiveness of different treatment modalities for the management of adult-onset granulosa cell tumours of the ovary (primary and recurrent)

Gurumurthy, M. et al Treatment modality, Granulosa cell tumours (GCTs), Ovary, Tumor Granulosa cell tumours (GCTs) of the ovary are rare ovarian tumours (2% to 5% of all ovarian cancers). Most ovarian tumours arise from the outer surface layer of the ovar ...

Exercise for Overweight or obesity

Shaw, K.A., Gennat, H.C., O'Rourke, P. and Del Mar, C. OBESITY, OVERWEIGHT, PHYSICAL ACTIVITY, WEIGHT LOSS, WEIGHT MANAGEMENT Overweight and obesity are important public health problems and are associated with many serious health conditions. The risk ...

Exercise-based rehabilitation for heart failure

Taylor, R.S., et al Exercise-based rehabilitation, Mortality, Hospital admissions, Morbidity. Quality of life Background People with heart failure experience marked reductions in their exercise capacity, which has detrimental effects on their activities o ...

Fixed-dose combination therapy for the prevention of cardiovascular disease

de Cates, A.N., et al Fixed-dose combination therapy, Fatal CVD, Non-fatal CVD, Bloodpressure, Lipid CVD, Risk factor, Prevention Cardiovascular diseases (CVD), including heart attacks and strokes, are the leading cause of death and disability worldwide. ...

Foam dressings for healing diabetic foot ulcers

Durnville, J.C., Deshpande, S., O'Meara S. and Speak, K. Diabetic foot ulcers Foot ulcers in people with diabetes are a prevalent and serious global health issue. Dressings form a key part of ulcer treatment, with clinicians and patients having many ...

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